Antiviral gene expression profiling of samples from Immunology RCT using Real-time PCR array system.

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Title of the project: Antiviral gene expression profiling of samples from Immunology RCT using Real-time PCR array system.

Duration of the project: July 2024 to July 2025

Study funded by: Ministry of AYUSH, Government of India

Arsenicum album is a homeopathic drug that was reported to show immune-modulatory effects and has been used for over 40 years to treat infectious diseases. It has been hypothesised that Arsenicum album modulates the immunological pathways related to innate and adaptive immune responses, inflammatory responses, and antiviral defence. To study in detail, a multicentric study in collaboration was conducted by the Central Council for 必威体育betway888 in Homoeopathy (CCRH), National Homoeopathy 必威体育betway888 Institute in Mental Health (NHRIMH), Translational Health Science and Technology Institute (THSTI) and 必威体育betway888 Institute of Virology (MIV) to better understand its benefits, cellular effects and toxicity. The study was conducted on 193 healthy patients who were given Arsenicum album 30C, followed by blood draws at regular intervals. The collected blood was tested for hepatic and renal toxicity studies, the PMBC isolated was used for immunological assays that were conducted at THSTI, and finally, immunological profiling using the serum/plasma samples (Real-time PCR array system) is currently ongoing at MIV. The findings might shed light on the potential of Arsenicum album as a preventative or supplemental medication to combat infectious diseases and strengthen the immune system in those at risk for serious infections.

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